Attributions

Conceptualization


The project has been ideated by our PI Dr Shamlan Reshamwala. Later on, through brainstorming Arya Gohad, Taha Umrethwala, Hrishabh Singh, and Darsh Vithlani further brainstormed and built on the project.

Project Administration


Planning and coordination of the project activities was done by Darsh Vithlani.

Background Research


An extensive literature search was performed by Hrishabh Singh, Darsh Vithlani, Taha Umrethwala, Arya Gohad, Shauryaraj Jilkar, Karanveer Singh and Swarali Paranjape to understand the biology of the 5’UTR and gene expression systems.

Investigation


The wet lab experiments are being conducted under the supervision, guidance and assistance of our instructor Prajwal Dongare. Darsh Vithlani and Swarali Paranjape have learnt the experimental protocols and carried out the work.

Analysis


Computational analysis of the experiments is handled by Hrishabh Singh. Harikrishnan Namboothiri is making a modest attempt to train neural networks on the data our experiments generate. Validation from literature, further developing the thought pipeline of the project was done by Arya Gohad, Hrishabh Singh and Darsh Vithlani in conjunction with Dr Shamlan Reshamwala.

Lab Maintenance


Cleaning, organizing and preparation of the research facilities has been done by Prajwal Dongare and Karanveer Singh.

Data Curation


The documentation of all the data generated in the wet lab is done by Prajwal Dongare, Karanveer Singh and Darsh Vithlani. The documentation of all the dry lab results is done by Hrishabh Singh and Harikrishnan Namboothiri. We thank Mayank Ghoghale and Shreya Shetty for their help in last minute documentation.

Fundraising


Approaching potential donors, companies and alumni, and negotiating with them through emails, calls or in-person meets was done by Kaustubh Wadekar and Ritesh Reddy Seri. Mihir Dakappagari and Darsh Vithlani assisted them wherever needed.

Entrepreneurship and Implementation Aspects


The proposed implementation was looked after by Kaustubh Wadekar, Karanveer Singh and Darsh Vithlani.

Public Engagement


The social media account of the team was managed by Darsh Vithlani. The design of templates wherever used for engagement was done by Vijayank Raj Chauhan. We have also developed a Monopoly Board game and a Gene Auction game. The concept of the games was developed by Arya Gohad, Karanveer Singh, and Darsh Vithlani. We thank Peehu Joshi and Jaysen Shah for their help in design of the same.

Software


The analysis of our data on OSTIR and RBS Calculator was done by Hrishabh Singh. Hrishabh Singh also modified the code of BioBrickIt which is software developed by one of our previous teams. Darsh Vithlani and Kaustubh Wadekar did NuPack simulation and made an attempt to understand the NuPack structures. We were assisted in this by our iGEM partner team IISER Behrampur.

Visualization


Preparation of content for the presentation of our work is being done by Arya Gohad, Hrishabh Singh, Kaustubh Wadekar and Darsh Vithlani. We thank Shreya Shetty for assisting us with the Wiki.

Writing


Reviewing and editing of the content for the Wiki and presentations is being done by Arya Gohad, Anirudh Veliyur, Karanveer Singh, Hrishabh Singh, Kaustubh Wadekar and Darsh Vithlani.

Safety


The safety aspects of the project were looked into by Prajwal Dongare and Darsh Vithlani. Our Primary Investigator Dr. Reshamwala is also a part of the Safety and Disposal Committee of our institute and we have been in compliance with all the norms.

Collaborators


We are highly grateful to the team of IISER Behrampur for all their help. We also thank our collaborators- iGEM Patras Medicine, iGEM Lanzhou University, iGEM IISER Thiruvananthapuram and iGEM IISER Tirupati.

Education


Education content was prepared and delivered by Arya Gohad, Sahil Jadhav, Darsh Vithlani and Dr. Shamlan Reshamwala. The lecture series organised was managed by Stuti Mishra and Aarya Darak. We are grateful for the assistance of Ishwari Joshi, Deepro Bandopadhyay and Stuti Mishra.
We are grateful to Mrs Sonali Kadam for helping to facilitate the Foldscope Workshop. We also thank Dr Anant Kapdi, Dr Archana Chugh, Dr Sunil Laxman, Dr Deepak Kumar Saini, and Dr Prasoon Kumar for their insightful lectures and time. We thank Mrs. Varsh Waghmare and Mrs. Meena Joshi for letting us organise lectures in the Tamil Medium School and Kendriya Vidyalaya respectively.

Sustainability Aspects


The Sustainable Development goals of our project were looked into by Anirudh Veliyur and Darsh Vithlani. We are thankful to Vaibhav Vishwanath and Ruchira Iyer for their guidance.
We are thankful to Mr. Ajay Vithlani and Shri Nilkanth Plastics for allowing to use their crusher when recycling our plastic tips. We are grateful to Dr. Sahai for helping us use extruder on our campus.

Human Practices


The work for human practices was carried forward by Gurpreet Bharj, Taha Umrethwala, Hrishabh Singh and Darsh Vithlani.
We appreciate and are truly grateful to Dr Joseph Wade, Dr Amanda Hughes, Dr Vito Giuseppe, Dr Narayan S Punekar, Dr Sarvanan Palani, Dr Rao Desirazu Narasimha, Dr Narendra Chirmule, Dr Deepak Modi, Mr Nilesh Kulkarni, Mr Abhishek Hule, Mr Soham D’Souza, Mr. Manish Mishra, Dr. Bhaskar Narayan Thorat, Dr. Ganpati Shankarling, Dr. Ashok Athalye for removing the time to give us valuable insights on our project which helped us and in our iGEM project and beyond in gaining further direction and broadened our horizons.

Mentorship


We thank Varshiny G for being our mentor throughout the trajectory of iGEM and for always being available for meetings whenever required. We thank the team of iGEM for their prompt responses whenever we had questions.

Gratitude Note


We acknowledge all our seniors who encouraged us to participate this year- Ninad Kumbhojkar, Supriya Prakash, Revathi Reddy, Chinmay Deshpande, Chinmayee Sarode, Aditya Kamat, Pritam Patil, Abhigyan Ray, Mihir Dakappagari, Ritoban Ghosh, Vaibhav Vishwanath, Ketaki Dhurve, Gurpreet Bharj, Swarali Paranjape, Ruchira Iyer, Ashvi Jain, Nupur Kale, Ruchi Thakur, Sai Tilekar, Tanvi Varadkar and Kareena Shah.

Special Thanks


We are highly grateful to our Vice Chancellor Prof Aniruddha B Pandit for always supporting us.

Our Sponsors


We would like to express our gratitude to our supporters Lupin Ltd and Aarti Industries. We also thank Mr Gokul Kaur for his generous donation. We further profusely thank Mr Sanjay, Mr Vikram Khanna, Mr Anvay Ukidve, Mr Ramasubramanian N and all our well-wishers for the generous donations through the ketto link. We thanl IDT for the fragments provided by them.