Hearing, as we know, is an animal's ability to perceive sound.It's the process of converting mechanical energy into electromagnetic signals. But the mechanism is not fully understood. BJWZ-China is trying to be the first to explore a similar sensory system in microbes. We set out to exploit the "NAN-IAV pattern" of ion channels that make up auditory mechanotransduction in Drosophila. In the experiment, it was introduced into Saccharomyces cerevisiae and the auditory module was constructed. We transformed the designed plasmid into Escherichia coli for amplification and culture, and then transferred into yeast for yeast transformation by plasmid extraction. Yeast DNA was extracted for PCR verification, followed by electrophoresis verification. Finally, the transformers were prepared and frozen in glycerol tubes. By studying this life phenomenon, we conducted the first round of research for the project of sensing cancer, and preliminary exploration for the subsequent research of sound transduction in microorganisms.

We are really glad to have shared this exhausting but unforgettable iGEM season with team BNU.
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