Project Description

Project Description


This project was motivated by reading an article about the current green algae problem in Korea (which has recently been intensifying). As it has a huge impact on odors and aesthetics, as well as aquaculture, drinking and agricultural procurement, the algae issue is not limited to Korea, but is more likely to be a global-level problem.

We learned that microcystin, a toxic substance produced by green algae, was detected in tap water in Korea. South Korea has world-class water purification technology, so we couldn't believe it. In addition, microcysitin has negative effects not only on humans but also on aquatic ecosystems, so we felt it require research approach in this point.

The four main factors that cause algae can be summarized as follows:

(1) Nutrients such as nitrogen and phosphorus
(2) High water temperature
(3) Strong sunlight (Insolation)
(4) Residence time

The main cause of algae is excessive use of nitrogen-phosphorus-potassium fertilizers. Nitrogen and phosphorus remaining due to excessive use of fertilizers flow into rivers through agricultural waterways, which was found to be the main culprit of eutrophication, the cause of green algae. Unlike the point source facilities such as drinking water treatment plants and sewage treatment plants, agricultural waterways, (which are non-point sources of pollution) are highly likely to be exposed to the risk of algae and eutrophication.

In this context, we focused on the vicious cycle in which Nitrogen and Phosphorus inflow into rivers due to excessive use of fertilizers causes algae, and the rivers in which the algae proliferate are reused for agricultural water. Therefore, our team decided to develop a Nitrogen treatment Bio Filter that can be easily installed and used by general farmers in private agricultural waterways.

Among Phosphorus and Nitrogen, Nitrogen was chosen for the following reasons: Phosphorus is a substance with a high possibility of causing various side effects by contributing to the phosphorylation process of various organisms. As it is a filter that is installed directly in the ecosystem, we tried to minimize the effect of the product of the metabolic process using Phosphorus on living things in other aquatic environments.

Hydrogen peroxide production


We have come up with several ways to solve the algae problem:

  • Ocher(Red clay)
Green algae can be removed by blocking sunlight, adsorbing phosphorus, (nutrient for algae) and coagulating and sinking surface algae. In fact, it is a existing method used in the short term to solve severe algal conditions in farms. However, the removal rate of green algae using red clay is less than 50%, and it is re-decomposed after it sinks and the algae could be regenerate.

  • Illite
In addition to its excellent antibacterial effect, Illite has the effect of removing algae by absorbing harmful substances and using high cohesive force. It removes toxic substances such as microcystin and adsorbs phosphate, one of the causative substances of green algae. However, since it is a mineral, it is difficult to mass-produce it, and so it had excluded from our project because it cannot be produced using synthetic biological methods.

  • Hydrogen peroxide
Hydrogen peroxide removes algae by destroying the chlorophyll of the algae. Using this method, after a certain period of time after mixing with water, it is separated into water and oxygen, there is no residual material, and it is possible to efficiently remove algae with a very small amount. The only problem is that it is a high-cost technology. However, if we use synthetic biology, we can produce Hydrogen peroxide in a relatively easy and economical way using only enzymes, so our team decided to use Hydrogen peroxide by introducing a method to compensate for the shortcomings of the substance in the filter.

Nitrogen removal


  • Anammoxosome
Anammox is a microbial metabolic process that plays an important role in the nitrogen cycle in many environments. In this process, NO2 and NH4+ are converted to N2 and water. The anammoxosome is one of the bacterial organelles that carry out anammox. So, our team thought about how to extract anammoxosomes from anammox bacteria and attach them to a biofilter for nitrogen removal. However, it was found that when the anammoxosome was extracted, the efficiency decreased sharply compared to when it existed as an organelle in bacteria. In addition, it was concluded that the process of culturing anammox bacteria was time-consuming, inefficient, and that the process of pure purification was not economical. So, our team devised a method to mass-produce each anammox enzyme in a cell-free way rather than extract anammoxosome.

Filter


There are three main ways to attach an enzyme to a filter. A method of physically attaching, a method of attaching using a covalent bond, and a method of capturing enzymes using a porous membrane. When we attach the enzyme to the filter, we need to consider 'Is it easy to attach', 'Is there permeability in the filter as metabolites must be transferred between the enzymes attached to the filter', 'Is the enzyme attached to the filter and the filter itself can it withstand the current of water?'. As a result of considering the above, our team adopted a method of capturing enzymes in a porous membrane. By using a special porous membrane, a large number of enzymes can be easily attached, and water can make contact with the enzyme as it passes through the membrane, making the desired process better.

Reference


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