One of the team leaders, responsible for the management of the whole team. He participated in the project design and implementation. He is responsible for experiments on adeno-associated viruses.
One of the student leaders, responsible for the daily management of the laboratory and team. She is responsible for the experimental design and implementation of the project, including the preparation of experimental equipment and the training of experimental members. She is responsible for the division of the experiment and participates in all the experiments of the project. She is responsible for writing and reviewing parts of wiki content and participates in human practice activities.
One of the student leaders, who is responsible for the daily management of the team. She proposed the preliminary design of the project. She was involved in the design and functional validation of the plasmid for REDMAP system. She also participated in the package of Adeno-associated virus (type 6, AAV6) and lentivirus, as well as experiments related to BC. She is also responsible for the contact between the experimental group and other groups and the project communication between the teams.
One of the student leaders, who is responsible for coordinating the work of the art desgin, wiki and publicity work, drawing scientific drawings such as road map. She also made customized team uniforms and cultural creations as well as financial reimbursement for the team.
He participated in the experimental operation of the blue-light activated cellulose degradation module.
He participated in the design of hardware and product application forms. He also participated in the molecular experiments such as the connection between bglx and plasmid, and the cell experiments of the function verification of red light suicide switch, and analyzed the data of these experiments and wrote a wiki.
She is responsible for the design of some red light control suicide module, and participated in the molecular and cell function verification experiments of BC membrane culture, AAV and red light control template; wrote the Design, Engineering, Results and Proof of concept sections of wiki website.
She participated in the construction of recombinant plasmid of adeno-associated virus and blue light—activated cellulose degration module. At the same time, she also took some photos.
He participated in the construction of plasmid of AAV assisted healing module and related experiments of blue light activated cellulose degradation module. He participated in the design and manufacture of hardware. He made a demonstration of the software. He is responsible for measuring and analyzing the physical properties of BC membrane and participated in the writing of wiki.
He participated in the experimental operation of healing promoting module and the blue light-activated cellulose degradation module.
She participated in the construction of plasmid of AAV assisted healing module and related experiments of blue light activated cellulose degradation module, and participated in the writing of wiki.
She is responsible for building experimental models.
She is responsible for drawing pictures and participated in the wiki design.
She is responsible for designing the brochure and participating in the wiki design.
He is responsible for building the wiki website.
She is responsible for the organization and practice of the entire human practice and educational activities, providing detailed planning and action guidelines for human practice and educational activities from the outset of the project, looking for suitable stakeholders and trying to get in touch with them to gain useful information and suggestions, designing and holding relevant educational projects, and so forth. She also participates in part of the experiment work.
She Zheng'an is a member from Human Practice group, who is responsible for the organization and practice of the entire human practice and educational activities. He designed and personally participated in many educational activities and try to let more people know about synthetic biology through educational activities. Furthermore, he is also responsible for writing the script of promotional videos, as well as writing and revising English manuscript.
He is a member of the Human Practice team and is responsible for the organization of teamwork, educational practices, and interactive activities. He has written a plan for many human practice activities, matched team members to create micro-videos together, let people around him spread synthetic biology knowledge to all directions, and can design small competitions to mobilize the enthusiasm of the public to learn biological knowledge.
He is our team's Primary PI. He attended each group meeting as scheduled. From experimental design to team building and management, he is always generous in providing us with valuable suggestions, and he has provided us with great help.
She is our team’s Secondary PI. She gave us a lot of advice in project conception.
They spare no effort to help us in project design and experiment. They are proficient in molecular, biochemical and cell biology knowledge and have rich experimental experience. Every time we have problems in the experiment, they will always analyze the experimental results with us and give reliable suggestions.
He helped us maintain a good laboratory environment, which is of great significance for us to produce good experimental results.
He discussed with us the heterologous expression of prokaryotic proteins in eukaryotic cells, the penetrability of red and blue light, lentivirus packaging, and the cellular compatibility of BC. At the same time, in the process of packaging and purifying AAV, he helped us solve the problems encountered in the experiment and analyze the experimental results. He attaches great importance to details and helps us design experiments clearly. We have benefited a lot.
Du Yunxi is one of the student leaders of BNUZ-China team in 2021. This year, she taught us about the operation and process of cell experiments in the laboratory, and answered our doubts in cell experiments.
They provided modeling inspiration for member of our modeling group, guided her to use modeling software and analysis data.
They introduced to us the firefighters' understanding and expectation of burn treatment, and shared with us the cases of colleagues who were unfortunately burned while performing tasks and the follow-up treatment. They introduced to us some popular science publicity activities that the Guangming District Fire Brigade will do daily, which has a great inspiration for us to design the popular science safety manual of fire knowledge and the popular science courses for primary and secondary school students.
The main component of Essex's core product is bFGF, a growth factor with excellent performance. Through communication with them, we learned about this previously unnoticed growth factor and decided to include bFGF in the BCAID project. After communicating with them, we also pay more attention to the safety of adeno-associated virus and the fixation of BC stent in the wound.
He shared with us the experience of using a certain scaffold product in clinical practice, suggesting that we should pay more attention to similar competitors in the market. According to the clinical operation process provided by Dr. Li, we determined the application scenario of BCAID, modified the application process of the product, and preliminarily designed the supporting hardware in the application process.
He analyzed the situation of existing products in the market for us and pointed out that we should work hard on product functionality and price efficiency ratio, which pointed out the direction for our project objectives. Under his inspiration, the healing promoting module was added to the project.
He introduced the detailed use process of wound stents to us, and helped us solve the problem of immune rejection that plagued us for a long time. Based on his clinical experience, he reminded us to pay attention to the antibacterial property of the product and suggested that we combine the application of BCAID with Vacuum Sealing Drainage(VSD). He gave us a lot of valuable advice.
In combination with the teaching practice, she introduced the understanding of middle school students on immunology, skin transplantation, burn treatment and synthetic biology to us, which has greatly promoted the design of education content. She provided some suggestions for the science popularization work of our project. The students in our team who participated in the summer volunteer education made curriculum design with reference to the suggestions of Mr. Wang, and achieved good science popularization effect.
He has rich experience in teaching and research, and introduced to us the overall knowledge of primary and secondary school students about burns and scalds. He put forward his own views on science popularization work, which are very helpful for our design to carry out science popularization activities.
SZPT-China has established a partnership relationship with us, and has carried out in-depth cooperation and mutual assistance in project conception, experiment, modeling, human practice, etc. We have held regular meetings and kept sincere communication.
BNUZH-China established a cooperative relationship with BNU-China last year, and we still maintain close contact this year. We discussed the project design and some experimental problems at the team exchange meeting.
We got acquainted with Peking in 2022 iGEM MeetUp in June, and then had in-depth communication with the Peking team. They told us that there are some details to be improved. At their suggestion, we changed the position of the gene in the plasmid; And added a purification label to the protein.
We continued the friendship with SZU-China this year. In the exchange meeting, SZU-China pointed out that the failure of our first co-culture experiment of cells and BC membrane may be due to the fact that the membrane is too thick and leads to the residue of alkaline substances and impurities. In view of this, we improved the sterilization process of BC membrane, and subsequently the experiment was successful. We sincerely thank SZU-China for their direct and effective comments.
They help our team with hardware design and physical manufacturing. They are not only our important external forces, but also our classmates with deep friendship. In the multi-party cooperation, we gradually developed multiple iterative versions of functional circuit boards, and manufactured hardware entities with 3D printing technology.
We cultured Acetobacter xlinum in the laboratory to obtain BC membrane, and then submitted the BC membrane sample to them. They measure some physical properties of BC according to national standards, helping us to characterize and analyze the products. According to the measurement data provided by them, we quantitatively analyze the product to better evaluate its performance.
Thanks for the laboratory support of the College of Education for the Future of Beijing Normal University at Zhuhai, the Center for Biological Science and Technology of Beijing Normal University at Zhuhai, and the Science and Engineering Experimental Platform of Beijing Normal University at Zhuhai.
Thanks for the great fundraising support from Beijing Normal University at Zhuhai.