Attributions

Committee Attributions

Oliver Loreto

  • Oliver wrote all of the code for the wiki, and was in charge of all the content going to the wiki. As wiki lead, he coded, edited and published every page. During the research phase, he did the initial literature exploration on ubiquitin and the biomarker UCHL1. As modeling lead, he directed the computational research group and evaluated the split ubiquitin/UCHL1 complex.

Arushi Singhal

  • Arushi worked on maintaining the project notebook, wet lab notebook, and experiment documentation in the wiki. During the research phase, she was in the biomarker research group and helped research binder controls for the golden gate assembly system as well as research into cell free systems. She also worked in wet lab to help prepare the plasmids for the control system.

Tulsi Patel

  • Tulsi was the Human Practices lead. She reached out to multiple personnel at the University of Oregon’s Athletic Medicine department, as well as other healthcare facilities on campus. She also created and managed a survey that asked respondents to share their concussion-related experiences. The results of this survey, along with the insight she received from personal interviews with professionals, provided valuable feedback for our project. Additionally, she assisted Keane in determining split complementation systems that could be used for our project.

Ava Komons

  • Ava worked with the human practices committee, helping with outreach. She also worked with the biomarker detection group, helping to collect data about our chosen biomarkers. She focused on finding biomarker controls and binder controls. She and Arushi came up with the biomarker control/binder combinations.

Peter Weisel

  • Peter worked with the human practices committee, helping with outreach. He also worked with the computational research group, evaluating GFAP binders.

Meaghan Smith

  • Meaghan worked as the Fundraising lead as well as helped with wet lab work and research for the biomarker group. During our fundraising efforts, she wrote grant applications, spoke with CEOs, coordinated with the social media team, oversaw efforts for various fundraising opportunities, and more. For the biomarker research, she assisted in researching biomarker expression in E. coli as well as the sequences used. Meaghan also assisted with wet lab work such as PCR, gel extractions, and miniprepping, to name a few. She, along with Addy, worked on the original idea for the project as a Synthetic Biology course project.

Adelin Alfred

  • Addy conducted wetlab work, helping pour plates and prepare media, as well as running several PCRs. During the research phase of the project, she worked with the biomarker research groups to determine the window of baseline physiological concentrations of our biomarkers and investigated possible off-target (not concussion-related) expression of our biomarkers. She also worked with the fundraising committee to solicit donations from UO departments. She and Meaghan developed the original idea of biomarker-based concussion detection via S100β for a class project.

Rose Hoang

  • Rose worked with the fundraising committee, helping to collect money to support our team. She also worked with the biomarker detection group, helping to collect data about our chosen biomarkers.

Theo Seah

  • Theo was the organization committee lead, helping to ensure our program went smoothly and safely. She also led the golden gate assembly group, going through research papers to figure out the best method to validate our split complementation systems. She assisted Carmen with designing primers and sequences for our design.

Keane Deas

  • Keane was in charge of researching complementation systems and signal readouts. He compiled a list of viable split proteins, evaluated them for their effectiveness in E. coli, analyzed each plasmid to determine protein construction, and tested substrates for infallibility in response to a metabolite-rich sample. Furthermore, he researched custom splitting a protein for active recombination using computational methods. In wetlab, he worked to prepare DNA from the IGEM distribution……

Oliver Loreto

  • Oliver wrote all of the code for the wiki, and was in charge of all the content going to the wiki. As wiki lead, he coded, edited, and published every page. During the research phase, he did the initial research on ubiquitin and the biomarker UCHL1. As modeling lead, he directed the computational research group and evaluated the split ubiquitin/UCHL1 complex.

Mindy Tran

  • Mindy was both the social media co-lead and the communications lead, in charge of recruitment, communications, and videography for the team. Mindy reached out, engaged, and brought in undergraduate students for the iGEM team through PowerPoints, classroom visits, and email blasts. She also wrote, directed, and edited the promotional video for the team.

Peter Weisel

  • Peter worked with the human practices committee, helping with outreach. He also worked with the computational research group, evaluating GFAP binders.

Alonso Cruz

  • Alonso worked on maintaining the team's social media presence, namely on Twitter. This included member spotlights, fundraising updates, and photos captured around the lab. He also met with Knight Campus Director of Communications, Lewis Taylor, to coordinate a collaboration between the Knight Campus Twitter account and the UOregon iGEM Twitter account.

Mindy Tran

  • Mindy was in charge of recruitment and videography for the team. She helped start this new team by reaching out and bringing in undergraduate students via informational PowerPoints, classroom visits, and email blasts. She also wrote, directed, and edited the promotional video for the team.

Carmen Resnick

  • Carmen led the experimental design for the complementation system, which included ordering and designing most of the DNA fragments and primers used in the experiments. She met with doctors and professionals to discuss the process and inform design of the study. Alongside her own contributions to the lab efforts and research, she facilitated the other students by connecting the various teams - computational, biomarkers, binders, and split proteins - in order to include everyone’s research in the final design. She also led lab trainings within the team, teaching various lab techniques to the other students.

Instructors, Advisors & PIs

Calin Plesa

Calin's contribution to our team was general mentoring and guidance on all aspects of the project.

Parisa Hosseinzadeh

As one of the PIs on the project, Parisa was involved in the initial brainstorming stages to help students narrow down their ideas and reach to their final project. She also provided general guidance to the computational group.

Anissa Benabbas

Anissa is one of the primary instructors of the UOregon iGEM team, as well as one of the founding members. Based on the students' scientific interests, she first helped them brainstorm and narrow down a research project idea. She then assisted students in gathering information for the project from various literature and patent searches, building a knowledge base that later enabled the students to design the project's concussion sensors. Furthermore, she also assisted with training for the wet lab portion of the project, as well as mobilized the team's fundraising efforts by connecting students with potential donors and leaders in philanthropy.

Justin Svensden

Justin assisted in training on wet lab techniques, computational modeling, and design of experiment for biosensor target selection. He was available for general questions and guidance throughout the project.

Noora Azadvari

Noora was one of the instructors, who helped shape and manage the team. Noora also mentored the computational part of the group to model the binders against our target of interest.

Others

Andrew Holston

Andrew helped with training team members to perform basic lab techniques and was available for questions.

Samuel Hinton

Sam ran our inital lab safety trainings and was available for questions about wetlab work and lab safety protocols.

Dr. Linda Lynch

Dr. Lynch worked helped the human practices committee to tailor our system to the needs of the emergency medicine community.