Increasing evidence has suggested that mitochondrial dysfunction is closely linked to the pathogenesis of ASD. Therefore, we designed two engineered probiotics to alleviate mitochondrial dysfunction by improving NAD+ concentration and eliminating heavy metals, as well as a drug delivery system for the probiotics. We also developed a L-lactate testing strip, allowing for convenient detection at home for autistic children with mitochondrial dysfunction.

In China, children with autism are also called “children from the star”, and our project, Engine of Starlight, guards the powerhouse, or the engine, of the human cells, the mitochondria, in these children, magnifying the light from them and their stars.