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Education and Communication

Overview

We are a bunch of people who love synthetic biology and iGEM. We hope to create a mass base for the development of synthetic biology. Therefore, we have carried out different forms of education for children, middle school students, college students and the public according to different ages. The aim is to let different basic populations, through explanation and education, understand the meaning of iGEM and synthetic biology, understanding its applications in medicine, agriculture, materials, the environment and energy. Triggering their interests about synthetic biology in life. Meanwhile we communicated to other teams from all over the world about our project to see if there are any room for improvement.

Education for children

Picture Book

In the early days of children understanding the world, they will be interested in the animals and plants, biological phenomena around them. They fully observe and fully perceive the nature, so they often ask a lot of " Why?” To satisfy the children's curiosity and stimulate their creativity, we recruited volunteers in cooperation with the Youth Volunteers Association of Beijing Institute of Technology. We jointly designed a picture book, "I Have, a Problem," featuring synthetic biology, hoping to solve most of children's questions.

In the picture book, we have designed five themes: The Origin of the Human Being, The Human Immune System, The Green Earth on Earth, The Smog and Dust Storm, and How Life Has Developed from Cells to Individuals. Among the "Human Origin" topic, we map how humans evolved from ape man for thousands of years to now us and how we get these evolution basis —— fossils. The "Human Immune System" topic, we map the processes of humoral and cellular immunity. To facilitate understanding, we compare antibodies to artillery shells, and simile B cells and T cells to police officers. On "Green on Earth," we show how forests, known as the lungs of the Earth, work and purify the air through photosynthesis. Anticipating that children can establish an awareness of protecting the forest. On the special "Smog and Dust Storm" topic, we draw the formation mechanism of two weather harmful to our health. How should we protect ourselves from illness in this weather, and advocate low-carbon travel for children. In the topic "How Life develops from cells into individuals", we map the process of gradually dividing fertilized cells into human bodies, giving children a preliminary understanding of our production, rather than staying at "I picked it from the trash can".

Through lovely pictures and small stories, we can arouse the interest of children. To let the children have a better understanding, we added Pinyin notes, and used a lot of metaphors to compared the biological professional knowledge to common things in children life. This can not only help them understand, but also let the children to learn in happy atmosphere and trigger their interested in biology. This is our original intention.

Here is our picture book~

Aid Education

iGEM2022-BIT-China Cooperated with Beijing Institute of Technology volunteer organization to Fangshan County Primary school volunteer teaching publicity.

In the summer of 2022, Hualiang Yue from iGEM2022-BIT-China and the volunteers of Beijing Institute of Technology, led by Miao Yu, a counselor of the School of Chemistry and Chemical Engineering, went to volunteer teachers in Fangshan County Primary School, Luliang City, Shanxi Province.

As early as the end of June, the volunteer teaching team began the preparatory work of —— previous volunteer teaching experience sharing, teaching plan preparation, course trial lecture, material preparation, etc. The team members make the best use of their talents and characteristics to accumulate strength for the volunteer teaching practice.

Teaching activities were held in the five days of July 18-22. In the volunteer teaching class, the young teachers,such as Hualiang Yue, were enthusiastic, bringing rich and interesting courses, spreading hope for the children's future. Children were taught scientific and interesting knowledge, such as the structure of cells, the origin of life and so on. The children listened carefully in class, took notes, showed their eyes for knowledge, responded actively in class, and participated in many experiments, saying that they were magical and interesting, and benefited a lot. Under the leadership of Hualiang Yue , they learned a lot of scientific knowledge of biology, chemistry and physics altogether.

HuaLiang Yue said very happy to give the children on such a popular science class, saw for a long time not see the children happy smiling face, feel their childlike innocence and lovely, a new generation of children and lively kind, and full of curiosity. HuaLiang Yue was willing to add wonderful color for the children's life. At the same time, we also received feedback from the children:

"Time flies, a little reluctant to give up, although the time is very short, we have gained a lot, very like you these teachers, I hope I can study like you in Beijing Institute of Technology.”

"These days are very happy and fulfilling. If you have a chance in the future, you are welcome to visit our school again.”

Online science popularization of Changping Middle school

Beijing Changping District No.1 Middle School, founded in 1951, is the first middle school in Changping district. It has always maintained the spirit of "unremitting self-improvement, integrity and loyalty", and has developed into a Beijing model ordinary high school with distinctive educational characteristics, and has become a banner of education development in Changping District.

On September 24,2022, Yuzhang Lun and Yiting Xing contacted the teachers of BIT team and Changping No.1 Middle School. Due to the epidemic, we had to give online lectures to the students of Beijing Changping No.1 Middle School and offline lectures within the university in the community.

First, the BIT team introduced the overview and project of their team. Then, Team BIT-China introduced the research ideas and methods of synthetic biology, the iGEM format, and our competition for this year and the "Oxygen Killer" (including inspiration, experiment, modeling, and human practice). Finally, I answered some questions from the students who participated in the lecture. For example, one student asked: Is a completely anaerobic environment easy to create in the laboratory? Does the completely anaerobic environment in biohydrogen production have an impact on cells? ( It will limit the activity of cells, so we want to build a low oxygen environment in cells under external oxygen conditions ). Some students have asked more questions about the "oxygen paradox", why does oxygen reduce some reaction efficiency? (Limiting the activity of some oxygen-sensitive enzymes.) Does the process of carbon sequestration then produce oxygen, which will in turn affect the efficiency of carbon sequestration itself? ( Some of the enzymes in carbon fixation are strictly anaerobic enzymes, and oxygen can inhibit the activity of these enzymes. Research hopes to avoid the influence of oxygen in the reaction, and design pathways that are not sensitive to oxygen.)

It was very meaningful that we held this presentation. First of all, we also learned a lot of ideas about experiment and human practice from the BIT team. Then, for the participants, most of them had not been exposed to synthetic biology before, and through our presentation, they learned more about some synthetic biology research ideas and IGEM. Inspiring more undergraduate and high school students to join synthetic biology is also one of the purposes of this presentation.

iGEM2022-BIT-China online popularization to Urumqi No.8 Middle School

After obtaining the consent of the teacher and the school, Xuanye Zhao , a member of the team, returned to his Alma mater—— Urumqi No.8 Middle School on July 26, and preached entitled "synthetic biology and iGEM Competition" to the school biology competition class of 2021. Owing to the fact that the audience has a certain contact to university biological knowledge competition and have a deep interest in biology, so I decided to tell some basic knowledge of synthetic biology at the same time, showing some biological knowledge in the field of scientific research and actual production application; and introduced the iGEM competition, this can shows the high school group of the world's top ten projects last year.

After introducing myself, I took the two problems encountered by my team in the brainstorming process as an example. The first one showed the students how to use the learned biological theory model to explain some special phenomena mentioned in high school textbooks, and tried to solve them from the perspective of synthetic biology. The students also enthusiastically guessed about the knowledge they have learned. Then I told my experience about the projects and subjects that I have done in college, so that they can know the process and mode of doing scientific research, and encourage them to continue their further study in biology. Finally, I introduced Beijing Institute of Technology to them, hoping that some of them can apply for our Beijing Institute of Technology this year. The happiest thing I experienced in my biology competition in high school was that we were able to be use more knowledge to solve my own questions or confusion. These little happiness in solving problems made me pass through the tiring high school and the college entrance examination, so I shared these fun with my classmates and sisters, hoping that they could still "make fun in pain" even under the high-pressure college entrance examination study.

Collage education

Recruiting Propaganda for Freshmen

On September 2,2022, Senior Yiyang Sun held a lecture in the community for Qiushi 2022 freshmen. This presentation is mainly a comprehensive introduction to IGEM. He introduced to the freshmen the different rules of iGEM Gold Award and silver Award and bronze award, the composition plate and what needs to be done in each section, and what are the gold medal projects in previous years. Prepare for the new team in IGEM2023.

iGEM2022-BIT-China works with the BIT team to popularize science for freshmen

On September 24,2022, the BIT-China team from Beijing Institute of Technology, together with the fellow BIT team, held an offline presentation in the community. We detailed the freshmen about the background of igem, synthetic biology, synthetic biology which is to build artificial biological systems that will run them like circuits. The initial synthetic biology used to formulate gene recombination techniques. As science continues to evolve, scientists have been limited to hard gene splicing, but to build genetic codes, hoping to build new organisms with synthetic genetic factors. Our project is also based on synthetic biology to build an intracellular low oxygen environment with normal metabolic efficiency, in order to solve the problem that certain oxygen concentrations will in turn limit the reactivity in some reactions. We highlight the background and inspiration of the team work, show the experimental work of the three modules of function, detection, and also briefly introduce the modeling work and other aspects of the work. Some students were very curious about our project, and asked them, how to build a low-oxygen environment in the laboratory (we showed them part of the experimental device, and briefly introduced the principle of the device). How have we met the bottleneck in our project? (we most directly contact our partnership, ask our advisor, or send an email message to relevant experts). How do we identify the most suitable species for the function module? (Through a large number of literature searches, and timely communication with seniors and teachers, and through the determination of experimental data.) Is leghemoglobin expression needed? (The addition of heme increases a certain amount of expression. Similarly, laccase contains copper, and when expressed, it is better to add some copper ions)

Social Education

Cartoon&Logo

iGEM2022_BIT-China Cartoon

As a form of artistic expression, comics have more affinity in the way of communication, It is universal, without regional and language customs, spreads a wide range, and can be broadcast on major social software. Therefore, the art group students drew some small cartoons inserted in the middle of the public account and ppt, and the five cartoons are made for the public of all ages. Therefore, the painting style of the cartoon is relatively simple and lovely. The key points of the biological knowledge to be explained are extracted through abstract or action description, part of the indescribable content supplemented by words, so as to achieve the purpose of promoting the biological knowledge of the cartoon. Therefore, the painting style of the cartoon is relatively simple and lovely. The key points of the biological knowledge to be explained are extracted through abstract or action description, part of the indescribable content supplemented by words, so as to achieve the purpose of promoting the biological knowledge of the cartoon. The biological knowledge in comic books looks more vivid and can help and guide thinking.

Part of our cartoon~~~

iGEM2022_BIT-China logo

The Logo ran through our presentation, every cultural and creative product, and it is inspired by the E. coli bacteria that will be used throughout the whole experiment. The image of Escherichia coli is lovely through an abstract personification, retaining the rough texture and flagella on its surface, and playing the role to achieve the purpose of the project. We add a fork or a torch, intended to use oxygen to achieve a low oxygen environment and to provide more convenience for people's lives. The main color of logo is blue and yellow with different meanings, blue symbolizes our understanding of low oxygen, yellow represents our expectations for the future.

iGEM2022-BIT-China works with Dingshi No.1 High School In the 798 Yue Art Gallery 2nd floor for the public publicity——The Synthetic Biology Carnival

We went to the Beijing 798 Yue ART GAllERY. The art gallery, the synthetic biology fair held here, is the offline project promotion activity we attend for the public in person without an online meeting , which is a biological crossover art exhibition. We not only communicate with other iGEM teams, sell our project products around, we also promote our project in the gallery.798 art area enjoys superb geographic location, with a good flow of people large traffic, which cover all ages, all kinds of professional, all kinds of cultural level . We face the people from primary school students interested in biochemistry to Peking University, to researchers graduating from China University of Geosciences , from those who are engaged in security but are interested in biology, to university teachers who come to see our exhibition. According to the different people, we also introduce different content.

When taking our display board on the subway, our display board has already attracted the attention of many people. Some people go to our display board to see the content of our display board, ask us about the content of the display board, and the purpose of taking the display board. We will also give them a brief introduction to what we are doing, introduce the iGEM competition, the content of our project, etc., and also send them our project products and welcome them to pay attention to the competition and follow our project.

For the primary school students, middle school students ,we mainly introduce biology, synthetic biology simple knowledge, and the content of biological ethics, laboratory safety problems, etc., some children are in the stage of scientific enlightenment, after listening to our explanation of biology,they are willing to learn more extracurricular knowledge after it. And the children were attracted by the lovely cartoon on our display board, took the initiative to ask us about it, the children vaguely understand, but let us feel good.

Many people also listened carefully to the introduction of our project and communicated with us. They are curious about how we determine the project topic, how to spend the period of stagnation in the project,.Someone will ask our professional questions, ask our attribution and also put forward constructive suggestions for our project. About our team personnel task assignment, they are sure we make great use of team resources and team members’ ability. Among them, someone from Peking University who was engaged in similar industries after graduation communicated with us a lot. He had enthusiasm for our participation in iGEM and our project topic selection have been fully affirmed.

In order to attract more people to know about our project, we will first send our project products —— masks, this move attracted a lot of parents with children, they hope the children come out to play at the same time also can learn knowledge. It let our project propaganda stage into the climax. Many children watched our exhibition board, brought the masks we sent out and asked us questions. We answered them enthusiastically and interacted with them. Both of us gained a lot of harvest.

Science Popularization Activity on Bilibili Station

We created our own account, BIT-China, on Bilibili station, and delivered our educational videos on it. We will be divided into five groups, each group in synthetic biology book to find a knowledge plate, writing and make ppt, and recording the video, we used the English subtitles, English, we in plain language knowledge of synthetic biology, let the audience know more about synthetic biology, hoping to inspire you life and synthetic biology thinking.

Science Popularization Activity on WeChat Account

We have created the public account called Synthetic Biology Little Assistant 2022, and published our educational video supporting copy and cartoon push on the public account, to complete the science popularization of synthetic biology.


Cultural and Creative Products

Cultural and creative products are a carrier of culture, and are interactive forms of new display combining with the latest technology. It not only deepens the awareness of cultural and creative products, but also integrates cultural and creative products into life. We have designed a variety of cultural and creative products, I hope someone can see our projects in our daily life, learn about iGEM, learn about synthetic tics, and become interested in it. This is the publicity effect of cultural and creative products.

①We designed the uniform: the front icon outer circle on the one hand combines circulation with biochemical elements such as test tube rack and detection tank, intended to show the meaning of synthetic organisms. It can not only bring more convenience to our lives, but also reduce the pressure of the environment to achieve the common will of sustainable development. On the other hand, it symbolizes the team's persistence and spirit of excellence and the better expectation of the project. Colorful colors not only symbolize the fruitful youth, but also symbolizes the colorful charm of the project. The three E. coli in the circle, one representing the guardian, one representing the optimistic, the other representing hypoxia, respectively correspond to the meaning of synthetic organisms, the spirit of the team, the project content. The icon on the back mainly extracts the book elements from the School of Chemical Engineering icon, plus an arrow into the book. It tended to show that we roam in the ocean of knowledge, to learn and explore. The jumping out E. coli means we can not only stay in the book knowledge, but also jump out of the book to practice to communicate and complete our project.

②We designed the mugs and file bags: The applied image is two jumping E. coli in blue and yellow, which would like to show the unity, optimism and positive of our team in the present. What’s, we hope to bring happy emotional impact to users.

③We have also designed the keychain blind box: It simply shows the versatility of the project, and in the form of the blind box can also attract more attention to our team and iGEM competition.

④Together with NAU-CHINA、BUCT-China to jointly designed face masks and postcards:In the current epidemic, masks have become an essential part of daily travel. Masks can protect ourselves and promote our project. More using of different team projects logo, can also show the not serious and rigid side of biochemistry. Also, considering people who like to mail letters, we printed some postcards.

Inclusiveness of members

Our team has a total of 20 undergraduates, they come from chemistry, chemistry, chemistry, computer, physics, English, economics and other different majors, different grades, have different gender and sexual orientation. The level of cognition of biology is even more inconsistent. The greatest thing in common as a group of non-biological students is our interest in biology.

In order to give you a more professional understanding of synthetic biology, our supervisor and graduate students first organized a three-month systematic study of synthetic biology knowledge. At the same time, students from different groups had various trainings (students in the modeling group conducted training on biochemical reaction modeling, and students in the experimental group conducted training on synthetic biology experiment skills).

After a certain knowledge base, each of us was brainstorming proposal planning. We voted together, and finally thought out a wonderful intersection [put a link to inspiration], forming our current project.

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The following is our interview with some team members on the relationship between their respective employment majors and project work:

Junchao Zhang (majoring in Information Technology): In my opinion, attending iGEM is just an interdisciplinary attempt for me personally. When learning as an information technology major, I often think about the application scenarios of the knowledge I have learned. In iGEM, I chose the modeling group and wanted to try to use what I have learned to solve some problems. Participating in iGEM has not only broadened my horizon, but also made me feel the role of information technology in basic science such as biology today. I think all the players in the same major as me have gained a lot from using information technology to solve practical problems in this iGEM event. In addition, team training is not a professional distinction, and I also had the honor to try some biological experimental operations that I had never experienced, which gradually aroused my interest in synthetic biology. These days in BIT-China were an unforgettable experience for me.

Jiashuo Lee (Major in Chemistry and Chemical Engineering): As the saying goes, "Biology and chemistry are not separated". As a chemistry student, I of course also have a strong interest in biology, and synthetic biology is originally a deep intersection of biology and chemistry. As an international competition in synthetic biology, iGEM has been caught my attention. It is both an opportunity and a challenge to join the BIT-China experimental team group for me. I am sure that I can gain an unusual experience in this team.

Rongyue Sun (An English major): I'm keen on chemistry and biology science since I was in high school. I would like to realize my unachieved Ideal through participating in IGEM competition in the light of my passion and the previous knowledge collected by observation and experiment. What's more, for the sake of anticipating to improve and ascend my level of professional knowledges in biochemistry, I deem that this is a good opportunity to have access to the most advanced technology and expand my personal dimensions in various orientations. Attending in translating works and can also let the English Knowledge I learned in collage be fully utilized. As an English major student, this is a good chance to apply my learning in both fields.

Zhiyue Xu (majoring in Environmental Design): As a student of environmental design, my major is not related to a wide variety of organisms, but also to the products of synthetic biology. I also have a certain curiosity about synthetic biology. I want the whole process of the iGEM competition to be closer to synthetic biology, to learn more relevant knowledge, and then apply it to life.

Inclusiveness of education

Our education is aimed at all levels of knowledge of all ages. We prepared for young children plain and fresh and lovely picture books, for middle school teenagers in China's most popular video website (known as "China pipeline") made a series of popular science video, for the university undergraduates (and BIT team) for synthetic biology and iGEM competition academic preaching, more popular during the 11 National Day in the Beijing museum of yue roadshow popular science activities.

Inclusiveness of the minorities

In terms of the art design of picture books, we specially made a choice of color, took care of the color-weak people, and launched a special Braille version..

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Inclusiveness of the language

In the preparation of picture books, we have not only Chinese and English versions, but also German, Spanish, Japanese and some small languages.

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Communication

Cmmunication with Worldshaper-Shanghai

On September 10, 2022, we were invited to participate in the project communicating activity hosted by the WorldShaper team. Mainly for project design exchange and expert advice.

In the exchange activity, we introduced the inspiration of the project from biological nitrogen fixation and hydrogen production, as well as the design ideas of our project. After the project introduction, Jiequn Wu , an expert at the meeting, put forward some suggestions for us.

In terms of modeling, oxygen mass transfer modeling is a key issue. In the future, it is possible to measure oxygen concentration in combination with exhaust gas mass spectrometry.

In the key issues of the project design idea, Mr. Wu mentioned that hemoglobin transfers oxygen to respiratory sites, promotes metabolism and oxygen consumption, which may lead to enhanced diffusion, and higher intracellular oxygen concentration. It is suggested that we can focus hemoglobin on specific subcellular areas. In this regard, we explain that leghemoglobin is different from VHb, which combines O2 and transfers it to the oxidative respiratory chain to ensure respiration and reductive reaction. According to the suggestions, we have also made the assumption of subsequent engineering iterations.

In terms of component selection, VHb natural promoters are also oxygen induced promoters, and we can also choose such natural components.

In the project introduction, the pet28a plasmid has a T7 promoter, and the lac inducible promoter needs to be written more clearly.

CCiC

From August 18 to August 22, 2022, we were invited to participate in the CCiC (Conference of China iGEMer Community), founded by ShanghaiTech_China, which is a good academic exchange platform for serving the vast iGEM community and for iGEMer and synthetic biology enthusiasts. It is one of the largest frontier academic exchange conferences for college students in China. Due to the epidemic situation, we were unable to arrive in Shanghai as usual. First, Ge Jiang, Vice President of Shanghai University of Science and Technology, and Nan Zhang, iGEM Headquarters delivered a speech at the opening ceremony. Later, they also participated in six keynote speeches in the field of synthetic biology. Five academic guests shared the positive design and construction of molecular programming using designed proteins, from gene editing to circular RNA vaccines, cell free synthetic biology, and gene circuits, Material synthesis biology: using the life editing function (living) materials, and Song Mingmin, the manager of the industry, shared the challenges and strategies of synthetic biology engineering. Through these lectures, we learned some technologies from the research fields of different doctors, such as designing egg white and protein circuits from scratch, making them encode information and program biological behavior in test tubes and cells, as well as gene editing technology New gene therapy and vaccine technology and high-throughput functional genomics technology, and pay attention to the molecular mechanism research of major diseases such as cancer and infection, quantitative and modular design of prokaryotic and eukaryotic gene expression regulation, computer-aided design of gene lines and applications, synthesis of microbial communities, etc. We also have a new understanding of synthetic biology. For example, the contribution of synthetic biology to the industry will be improved, and there will be more economic output in the future. In the face of the sustainability of bioenergy, synthetic biology is a powerful weapon.

On August 19, after the completion of the experimental design, we reported the contents of the team and participated in several team exchanges. We learned about the focus of each track of synthetic biology and the advanced research techniques used by different teams, such as using biological principles and mathematical tools to design software and hardware for biological components. We have also received a lot of guidance and suggestions from experts in various fields, such as the direction of enterprise cooperation, the use of modeling work to optimize the contribution proportion of several different hypoxia programs, etc. We also learned about CPU_ China and Shanghai Tech China have provided many suggestions for our follow-up experiments.

In addition, we also actively participated in CCiC's knowledge contest on daily activities. Small biological problems made the atmosphere of the conference relaxed and pleasant.

In September, we received souvenirs from CCiC and the listing of participants. The "LIFE SCIENCES ASSEMBLY US iGEMERS TOGETHER" clarifies the original intention of CCiC activities, that is, we are college students from all over China who love synthetic biology. We all hope to make contributions to human life with our modest efforts. This competition makes us meet and our thoughts collide in communication. Finally, I would like to thank CCiC for providing us with such a platform.

NJTech-China

In this year's project, we worked with NJTech-China, a team from Nanjing University of Technology.

In May, we learned at a project idea exchange meeting that NJTech_China, which is the project in this year. We has some similarities which is also related to oxygen metabolism. Their project inspiration is that there are some Fe-S cluster proteins and other substances in anaerobic organisms that are easy to be destroyed by active oxygen, which is also the reason why anaerobic bacteria do not grow well in aerobic environment. Introducing some elements into anaerobic bacteria to regulate oxidative stress can enable anaerobic bacteria to have certain viability under aerobic conditions.

In September, we communicated about the progress of the experiment again. We use the nirB promoter, while Nanjing University of Technology uses the Vitreoscilla haemoglobin promoter (vgb promoter) that we have also been exposed to before. Both promoters can play a role in hypoxia induction. They considered the activation of FNR on vgb promoter, and improved vgb promoter around this, and hoped to use this promoter to control the expression of oxidative stress protein under different oxygen concentrations. Since we all chose anaerobic inducible promoters, they shared their literature with us and discussed the mechanism of several anaerobic inducible promoters.

They mentioned that the fluorescence data of four modified vgb promoters expressing fluorescent proteins are being tested in the experimental part. At this time, our team is also measuring fluorescence data, hoping to get experimental data.

For the modeling part, we mentioned that the data is slightly insufficient, and we need to use gray prediction and other methods to operate. Nanjing University of Technology also mentioned that the data is not enough, and their modeling feeling is biased towards prediction, expecting to guide the next transformation direction.

In the submission of the Parts website, we exchanged details. The nirB component we submitted does not meet several principles in the web page. The students of Nanjing University of Technology gave a detailed explanation and shared their experience on matters needing attention in codon optimization.

Finally, we asked Nanjing University of Technology how to create a hypoxic environment. Our team lacks relevant experimental equipment, so we temporarily choose anaerobic bag for operation. Nanjing University of Technology chose a special anaerobic incubator. Clostridium tyrobutyricum is the strictly anaerobic site microorganism they selected, but it is difficult to cultivate, so they first chose Escherichia coli as the chassis organism. When they used E. coli, they also used the culture medium to fill the container to enhance hypoxia.

Syn bio fair

Due to the impact of the epidemic, most Chinese teams cannot go to Paris, France, to participate in offline Jamboree this year. iBowu China joined hands with the cyanobacteria studio to launch offline mini Jamboree in Beijing.

As a university in Beijing, we are very grateful for meeting this exhibition. We can communicate our projects offline with more teams, which can make up for our regret that we cannot experience Jamboree offline. With a feeling of expectation, we have made a lot of preparations for this exhibition - the Chinese and English version of the project introduction board, the surrounding areas of the project, etc.

On the afternoon of October 7, we met with several other teams in the Yue Art Museum of Beijing 798 Art Center.

We first visited the BJEA China exhibition. The theme of BJEA is: the fight for plastics in the deep sea. The combination of BslA and mPETase breaks the shackles of plastics on biology. They said that the large-scale use of plastics has caused great environmental pollution. A large number of plastics enter the sea and return to our dining table, causing great harm to mankind. They are committed to the recycling and degradation of plastics. In the experimental part, they found that 97% PET was decomposed by enzymes found naturally in composting, and their main work was to improve the activity of biological PET recycling process. In the process of searching the literature, they found that mutant LCC is the most effective enzyme for degrading PET. In social practice, they published an article on the official WeChat official account of Beijing International Environmental Protection Agency to expand their influence. They also did a lot of hand painting to decorate their experimental part, which is convenient for readers to immerse themselves. During the communication, we found that they have many good things we can learn from, such as improving the interest of the experimental part of the website to attract more readers, and strengthening the connection between the project and the environment.

Later, we visited iBowu China. In the experimental part, they expected to design a drug that could effectively inhibit the recurrence of bladder cancer. They plan to produce highly active Lon protease from Escherichia coli this year and use it to design a drug to improve the surgical prognosis of bladder cancer patients with overexpression of C-myc gene. We learned more about their human practice. They designed a lot of projects around. They also released a version of their own script No body, no case. Their surrounding publicity work is worth learning.

The experimental design of the cooperative team of iBowu-China is to protect the eyes with anthocyanins. Anthocyanins are used to replace traditional methods to dye the beautiful eyes to reduce the damage of the beautiful eyes. We also observed their small dyeing experiment and got some inspiration from the experiment.

The two teams came to visit our exhibition site, and we mainly introduced the background of the project, experimental modules - function and detection, modeling, application and human practice. And we showed them the perimeter of our project - masks, mugs and keychains. We talked about the progress and difficulties in the experiment. We all paid more attention to this mini Jamboree because there was less offline human practice of the epidemic. We also exchanged some surroundings of each team.

Then we met members of Tsinghua-iGEM. Their experiment is expected to design a sperm test that can be completed at home. They mentioned that in the past 40 years, the number of sperm in the world has declined significantly, and sperm quality is a very important issue for the next generation and the future of mankind. However, due to the sense of shame and fluke, it still lacks public awareness. We also watched the project promotion video made by them, and learned about the principle and process of sperm detection. We also introduced our project inspiration and experimental progress to them. We exchanged some information about iGEM support and team recruitment in the school. Both Beijing Institution of Technology and Tsinghua University attach great importance to iGEM. Every year, there are special lectures in the Academy to introduce iGEM and recruit new students. We all need very strict interviews to become members of iGEM.

We benefited a lot from the three hour exhibition exchange, both from the experimental part and how to better carry out human practice during the epidemic. In the context of the epidemic, we were unable to go abroad to participate in the offline Jamboree, and this team exchange meeting made up some regret to some extent. Each team is doing their best to make the project more colorful.