Our Contributors
Mrs. Erinn Eddingfield
Mrs. Eddingfield teaches chemistry and anatomy at Canyon Crest Academy and helped our team with the logistics of registration and club maintenance as our primary PI.
Canyon Crest Academy Foundation
The Foundation at our high school generously aided us with registration payment for the iGEM competition and Jamboree. We also worked with them to host our summer STEM camp. Thanks to Mrs. Couvrette, Mrs. Mahmood, and Mrs. Vaughn for all of the help that they gave us this year.
Dr. Conor R. Caffrey
Dr. Caffrey—a Professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences and senior scientist at the Center for Discovery and Innovation in Parasitic Diseases—provided his expertise in the schistosome pathogen and offered guidance through much of the season, which has been integral to our project in terms of environmental safety, antischistosomal effectiveness, and implementation. The CCA team is extremely grateful to him and his efforts to produce the data regarding the activity of our antischistosomal compounds against live Schistosoma mansoni sporocysts.
Dr. Yo Suzuki
Dr. Suzuki, Assistant Professor of Synthetic Biology at the J. Craig Venter Institute, allowed us to use lab space and materials this iGEM season and made our entire wet lab possible. We are very grateful for all that Dr. Suzuki and JCVI have done for us these past two seasons.
Dr. Joshua Widhalm
To get a better understanding of plumbagin, we met with professor Joshua Widhalm from Purdue University. Dr. Widhalm provided solutions on how to utilize plumbagin without toxicity as an environmental issue.
Dr. Sharon Reed
Dr. Sharon Reed is an infectious disease specialist at UCSD Health. She also does research on antiparasitic drugs, which we were interested in learning more about. As a physician with firsthand experience in schistosomiasis, Dr. Reed provided us with detailed information about its diagnosis and symptoms.
Dr. Si Ming Zhang
Professor Si-Ming Zhang works at the University of New Mexico and researches snail intermediate host and schistosome parasite interactions. In the beginning stages of our research, we were lacking information about the actual snails themselves and their life cycles, so we contacted Dr. Zhang for a meeting.
Dr. Elizabeth Winzeler
Professor Elizabeth Winzeler works in the division of Pharmacology and Drug Discovery, as well as the department of Pediatrics and translational research at the UCSD Health Sciences Center for Immunity, Infection, and Inflammation. We contacted her because of her expertise in malaria drug discovery for both prevention and treatment.
Dr. Karin Fester
Dr. Karin Fester works at the University of Leipzig in the Institute of Pharmacy. As a phytochemist, she published a paper on an attempt to produce plumbagin in E. coli; however, it did not work initially because they did not have the full biosynthetic pathway down due to missing enzymes. One of our team members encountered Dr. Fester's paper and found it very relevant and insightful to our current project, so we contacted her to see if she would meet with us.
Dr. Winka Le Clec'h
Dr. Winka Le Clec'h is a staff scientist at the Texas Biomedical Research Institute. Because of her work in schistosome drug resistance, she is an expert in snail-schistosome interactions—information that we lacked.
Dr. Larissa Podust
Professor Larissa Podust conducts pharmaceutical research at UCSD. As a structural biologist, we were interested in her research of drugs targeting parasitic diseases. At the time, we didn't have much information on how the compound itself would work, and had mainly focused on its production.
Mrs. Dvora Celniker
Mrs. Celniker aided us in our hardware development. She provided us the resources to 3D print the parts necessary for the eco-plates and bioreactor.
iGEM Impact Grant
The iGEM Impact Grant allowed us to attend the in-person Jamboree, even when we could not find many financial sponsors this season.
Student Attributions
| Claire Kang | Andrew Tsui | Emily Han | Hans Yang | Ishan Deshpande | Matthew Song | Shruti Malladi | Melinda Chang | Amy Wang | Bruce Bei | Quyen Ho | Sophie Chung | Katherine Kwon | Amogh Chaturvedi | Noah Zhang | Riya Irigireddy | Alma Razavilar | Emily Zhang | Danica Diva | Jonathan Deng | Rithika Kapila | Weili Jin | Saanvi Rao | Dale Deng | Trisha Thontepu | John Park | Laya Vijayanand | Narayana Hillam | Nivi Chozhan | Jitendrakumar Jeenagala | Ritvik Irigireddy | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Scicomm & HP | Summer Camp | |||||||||||||||||||||||||||||||
| Bacteria Book | ||||||||||||||||||||||||||||||||
| Children's Book | ||||||||||||||||||||||||||||||||
| YouTube Channel | ||||||||||||||||||||||||||||||||
| PSA Website | ||||||||||||||||||||||||||||||||
| Implementation | ||||||||||||||||||||||||||||||||
| Policy Review | ||||||||||||||||||||||||||||||||
| Survey Analysis | ||||||||||||||||||||||||||||||||
| Promo Video | ||||||||||||||||||||||||||||||||
| Ethics Symposium | ||||||||||||||||||||||||||||||||
| Wiki | Web Design | |||||||||||||||||||||||||||||||
| Graphics | ||||||||||||||||||||||||||||||||
| Lab | Plasmid Design | |||||||||||||||||||||||||||||||
| Expression Procedures | ||||||||||||||||||||||||||||||||
| Compound Research | ||||||||||||||||||||||||||||||||
| Snail Proof of Concept | ||||||||||||||||||||||||||||||||
| Yeast Proof of Concept | ||||||||||||||||||||||||||||||||
| Parts | ||||||||||||||||||||||||||||||||
| Modeling | Bioreactor | |||||||||||||||||||||||||||||||
| Eco-plate | ||||||||||||||||||||||||||||||||
| Toxicity Modeling | ||||||||||||||||||||||||||||||||
| Anti-schistosomal Modeling |