The “cutting edge” of probiotic science now consists of cramming as many CFU into a single pill as possible, in hopes that it will improve colonization of the gut.
Most probiotics will also make a blanket claim of “good for gut health”, but what does that even mean?
The gut microbiome is like a fingerprint, different from person to person. Not just that, gut microbiomes change frequently, and microbiomes will look different from one week to another.
Due to this, probiotics have a hard time colonizing consistently, and if all the positive effects of the probiotic rely on this mechanism, then by extension the probiotic will be inconsistent in providing a positive effect.
This year, the McGill iGEM team set out to disrupt the probiotic industry by creating a probiotic designed in such a way that does not rely on colonization to work.
Once a patient already develops cardiovascular disease due to high cholesterol, it is difficult to treat. However, healthy people who do not any symptoms of high cholesterol will be unwilling to take prescription medicine to control cholesterol levels due to the slew of side effects.
To avoid the serious dangers of high-cholesterol, people need a way of managing cholesterol early on in their lives.